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Transferrin Saturation Formula:
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Transferrin Saturation (TS%) is a medical laboratory value that represents the percentage of iron-binding sites on transferrin that are occupied by iron. It is a key indicator of iron status in the body and helps diagnose various iron-related disorders.
The calculator uses the Transferrin Saturation formula:
Where:
Explanation: The equation calculates what percentage of the total iron-binding capacity is actually occupied by iron, providing insight into the body's iron availability.
Details: Transferrin Saturation is crucial for diagnosing iron deficiency anemia, iron overload conditions like hemochromatosis, and monitoring iron therapy. Abnormal values can indicate various metabolic disorders.
Tips: Enter serum iron and TIBC values in µg/dL. Both values must be valid (greater than 0). For accurate results, use fasting morning samples when possible.
Q1: What is the normal range for Transferrin Saturation?
A: Normal TS% ranges from 20-50% in most adults, though ranges may vary slightly between laboratories and populations.
Q2: What does a low Transferrin Saturation indicate?
A: Low TS% (<20%) typically indicates iron deficiency, which can be caused by inadequate intake, malabsorption, or chronic blood loss.
Q3: What does a high Transferrin Saturation indicate?
A: High TS% (>50%) may indicate iron overload conditions such as hereditary hemochromatosis or excessive iron supplementation.
Q4: How does TS% differ from ferritin?
A: While ferritin measures iron stores, TS% reflects the circulating iron available for use by the body. Both tests provide complementary information.
Q5: When should Transferrin Saturation be tested?
A: TS% should be tested when iron disorders are suspected, when monitoring iron therapy, or as part of a comprehensive iron panel for diagnostic purposes.