1. What is Transferrin Saturation?

Transferrin Saturation (TS%) is a medical laboratory value that represents the percentage of iron-binding sites on transferrin that are occupied by iron. It is calculated from serum iron and total iron-binding capacity (TIBC) measurements.

2. How Does the Calculator Work?

The calculator uses the Transferrin Saturation formula:

Where:

• Serum Iron — Measured iron concentration in the blood (µg/dL)
• TIBC — Total Iron-Binding Capacity (µg/dL)

Explanation: This calculation shows what percentage of the iron-binding capacity of transferrin is actually occupied by iron.

3. Importance of TS% Calculation

Details: Transferrin saturation is an important indicator of iron status in the body. It helps diagnose iron deficiency anemia, iron overload conditions like hemochromatosis, and monitor iron therapy.

4. Using the Calculator

Tips: Enter serum iron and TIBC values in µg/dL. Both values must be valid (greater than 0). The result will show the transferrin saturation percentage.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal transferrin saturation range?
A: Normal TS% is typically 20-50% for men and 15-50% for women. Values below this may indicate iron deficiency, while values above may suggest iron overload.

Q2: How is this different from serum ferritin?
A: While TS% measures circulating iron, ferritin measures stored iron. Both tests provide complementary information about iron status.

Q3: When should TS% be measured?
A: It's typically ordered when iron deficiency or iron overload is suspected, or to monitor treatment for these conditions.

Q4: Are there limitations to this calculation?
A: TS% can be affected by inflammation, liver disease, and other conditions. It should be interpreted in clinical context alongside other iron studies.

Q5: How often should TS% be monitored?
A: Frequency depends on the clinical situation. For iron deficiency treatment, it might be monitored every 3-4 months; for hemochromatosis, more frequently during initial treatment.